What is Levosulpiride
Levosulpiride is a substituted benzamide antipsychotic, reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent.Levosulpiride is also claimed to have mood elevating properties.
Levosulpiride Mechanism of Action
Levosulpiride is a substituted benzamide, which exerts antidopaminergic (selective dopamine D2 receptors) activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent.
Oral bioavailability is about 30%; peak plasma concentrations after about 3 hr.
Mainly via urine. Plasma half-life: 9.7 hr (oral); 4.3 hr (IV).
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