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Pharmaceutical Peptide Thymosin Alpha1 Acetate for Chronic Hepatitisb CAS 62304-98-7

Purchase Qty.:
(vial)
5-49 50+
FOB Unit Price: US $1.8 US $1.3
Purchase Qty. (vial) FOB Unit Price
5-49 US $1.8
50+ US $1.3
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Production Capacity: 5 Tons/Years
Transport Package: Disguised
Payment Terms: L/C, T/T, Western Union, Money Gram, Bitcoins

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Basic Info
  • Model NO.: 62304-98-7
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Grade: Pharmaceutical Grade
  • Ms(Esi): C129h215n33o55
  • Use: Muscle Growthing
  • Specification: white powder
  • Powder: No
  • Certification: GMP, ISO 9001, USP, BP
  • State: Powder
  • CAS: 62304-98-7
  • Alias: Consistent
  • MW: 3108.3
  • Trademark: SENDI
  • Origin: China
Product Description
Product Description:

Name: Thymosin α1 Acetate
Alias : Thymosina1 (ox), Thymalfasin, Thymosina1 (human), Zadaxin, Thymosin α1, Thymosin, Alpha 1, thymosin а1
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >=80.0%
Water Content(Karl Fischer): <=5.0%
Specific Rotation (20/D): -95.0~-105.0°(c=0.5 1%HAc)
Acetate Content (HPIC): <=15.0%
MS(ESI): Consistent
Mass Balance:95.0~105.0%
Storage: Closed, below 2 ~ 8ºC preservation 

Usage : This product is mainly used for the treatment of chronic hepatitis B immune strengthening agent. Thymosin Alpha-1 is being researched for the treatment of Hepatitis B and C, and it is also approved for inclusion with vaccines to boost the immune response in the treatment of other diseases.
 
Description
 
Thymosin α1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene. Thymosin Alpha-1 is a component of Thymosin Fraction 5 responsible for restoring immune function in animals lacking thymus glands. It was the original peptide synthesized from the Thymosin Fraction 5. Unlike β thymosins, which are genetically and chemically unrelated, Thymosin α1 is produced as a 28-amino acid peptide fragment from a longer, 113-amino acid precursor,prothymosin alpha. Research has shown it to enhance cell-mediated immunity in experimental animals and research subjects.
 
Thymosin Alpha-1 is being researched for the treatment of Hepatitis B and C, and it is also approved for inclusion with vaccines to boost the immune response in the treatment of other diseases.

Application:
 
Thymosin α1 is now approved in 35 under developed or developing countries for the treatment of Hepatitis B and C, and it is also used to boost the immune response in the treatment of other diseases.
Exhibiting a variety of immune regulating properties, thymosin-alpha-1 induces differentiation of murine T-cell precursors and human thymocytes and the terminal differentiation of functionally immature cord blood lymphocytes and induces production of IL-2, high affinity IL-2 receptors, and B-cell growth factors by peripheral blood mononuclear cells. T-helper and cytotoxic/suppressor T-cell populations are targets of thymosin activity.

Thymosin-alpha-1 has been shown to increase the efficiency of antigen presentation by macrophages and to be an endogenous modulator of alpha-thrombin activity.


Specification:
 
Product NameThymosin α1 Acetate
Cas No.62304-98-7
Molecular FormulaC129H215N33O55
Molecular Weight3108.3
Purity (HPLC)98.0%min.
AppearanceWhite powder
Single Impurity (HPLC)1.0%max
Amino Acid Composition±10% of theoretical
Peptide Content (N%)≥80.0% 
Water Content(Karl Fischer)≤5.0%
Specific Rotation (20/D)-95.0~-105.0°(c=0.5 1%HAc)
Acetate Content (HPIC)≤15.0%
MS(ESI)Consistent
Mass Balance95.0~105.0%

Thymosin Alpha-1 is a component of Thymosin Fraction 5 responsible for restoring immune function in animals lacking thymus glands. It was the original peptide synthesized from the Thymosin Fraction 5. Unlike β Thymosins, which are genetically and chemically unrelated,

Thymosin α 1 is produced as a 28-amino acid peptide fragment from a longer, 113-amino acid precursor, prothymosin alpha. Research has shown it to enhance cell-mediated immunity in experimental animals and research subjects...

Thymosin Alpha-1 is being researched for the treatment of Hepatitis B and C, and it is also approved for inclusion with vaccines to boost the immune response in the treatment of other diseases.
Exhibiting a variety of immune regulating properties, thymosin-alpha-1 induces differentiation of murine T-cell precursors and human thymocytes and the terminal differentiation of functionally immature cord blood lymphocytes and induces production of IL-2, high affinity IL-2 receptors, and B-cell growth factors by peripheral blood mononuclear cells.

T-helper and cytotoxic/suppressor T-cell populations are targets of thymosin activity. Thymosin-alpha-1 has been shown to increase the efficiency of antigen presentation by macrophages and to be an endogenous modulator of alpha-thrombin activity.
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