Etoricoxib Powder CAS202409-33-4 Pharmaceutical Raw Materials
|10-49 50-99 100+|
|FOB Unit Price:||US $5 US $2.5 US $1|
|Purchase Qty. (grams)||FOB Unit Price|
|Payment Terms:||T/T, Western Union, Paypal, Money Gram, BITCION|
- Model NO.: 315-37-7
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Quality Standard: USP
- Transportation: DHL, UPS, TNT, EMS, FedEx or Other
- Assay: 99.9%
- Transport Package: 1kg/Bag, 100grams/Bag, 10grams/Bag
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001, Ep5
- State: Solid
- Appearance: White Powder
- MOQ: 10g
- Assay Way: HPLC
- Trademark: Sendi
- Specification: 1kg/bag, 100grams/bag, 10grams/bag
- HS Code: 3001200010
Etoricoxib (Arcoxia) is a selective COX-2 inhibitor from Merck & Co. Currently it is approved in more than 80 countries worldwide but not in the US, where the Food and Drug Administration (FDA) has required additional safety and efficacy data for etoricoxib before it will issue approval.
What is Arcoxia?
Arcoxia is used for the following:
acute and chronic treatment of the signs and symptoms of osteoarthritis and rheumatoid arthritis
management of ankylosing spondylitis
relief of chronic musculoskeletal pain
relief of acute pain
to treat acute gouty arthritis
How does Arcoxia work?
Note: Arcoxia has not been approved by the FDA for the U.S. market.
Arcoxia belongs to a group of medicines called cyclooxygenase-2 (COX-2) specific inhibitors (also known as coxibs).
The body produces two similar enzymes called COX-1 and COX-2. COX-1, among other functions, is involved with protecting the stomach, while COX-2 plays a role in joint inflammation and pain.
Arcoxia reduces pain and inflammation by blocking COX-2, an enzyme in the body.
Arcoxia does not block COX-1, the enzyme involved in protecting the stomach from ulcers.
Other anti-inflammatory medicines (NSAIDS) block both COX-1 and COX-2.
Arcoxia relieves pain and inflammation with less risk of stomach ulcers compared to NSAIDS.
However taking aspirin with Arcoxia may reverse this benefit (see Before you take Arcoxia, Taking Other Medicines).
|Appearance||White to 0ff-white powder|
Residue on Ignition
|Related substances||Single biggest impurity≤0.1%|
Etoricoxib is indicated for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain, and gout. Approved indications differ by country .
A Cochrane systematic review assessed the benefits of single-dose etoricoxib in reduction of acute post-operative pain in adults. Single-dose oral etoricoxib provides good quality pain relief post-operatively in adults and adverse events are similar to placebo in the studies included. Etoricoxib given at a dose of 120 mg is as effective or even better than other analgesics that are commonly used .
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